Cort RX by ATP Science 90 capsules

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CortRX

CortRX is a product that contains Schisandra, Turmeric, Rhodiola, and Ashwagandha.

CortRX is a powerful combination of adaptogenic herbs designed to help you deal with stress and adapt to the situation at hand via helping support the normal function of the HPA axis. By balancing stress and promoting normal cortisol levels, you may experience improved sleep patterns and maintain healthy inflammatory response and it may help to maintain normal cortisol levels. Thankfully, our modern-day stresses are more bills and less lions and tigers*.

If we’re getting chased by a tiger; massive amounts of adrenalin and cortisol would have been released by the body so we could (hopefully) outrun or outfight the beast. If we didn’t have that response, we would have been the big cat’s lunch; and of course, then not had a chance to make babies. This is partly why there are so many people suffering from stress in the world. You inherited a survival technique that is ideal for surviving acute life-threatening stress but may not be the most efficient way to deal with a troll, a text, bills, public speaking, crowds, or that boss on your back.

How we react to stress

Nowadays, most of us aren’t being chased by big cats but our genes are still programmed that way. The ‘beast’ chasing us today is chronic stress, the long-term daily grind, and constant exposure and unavoidable stress unlike the Tiger’s ‘minutes’ of acute intense stress.

Each time, regardless of the trigger we release neurotransmitters (such as noradrenaline) and hormones (in particular cortisol) that catalyze a series of events that help us deal with the challenge. Cortisol is a very interesting hormone as it helps with the survival response through various mechanisms like increasing blood sugar and blocking relaxation and sleepy chemicals (serotonin)[iii] but then it has a “negative feedback” effect, letting the body know that you had a stress response and can now switch off and relax.

The problem is with modern life there is constantly one form of trigger or another so there is a constant stimulus to pump out these stress chemicals. Chronic exposure to a powerful hormone like cortisol can increase fat gain.[iv]

Yet here we are with the mortgage, stressful job and even environmental stress we simply can’t escape. We just have to manage these unavoidable stressors better.

The hormonal fluctuations

To fully understand how to influence hormonal secretions and activities we must first understand the big picture and know the natural cycles that dictate our body’s priorities between thriving or surviving. The Hypothalamus in our brain collects data from our body to inform of potential stressors.[v] Our body can’t afford to wait and see if something is life-threatening before it reacts, therefore it will trigger a stress response, proactively, just in case. The immune system, inflammatory chemicals, emotional stress, fear, pain, temperature extremes, toxicity, training hard, caffeine, etc. will all activate the Hypothalamus to initiate a survival response. The end result is that the hypothalamus sends this stress message to our pituitary gland, which then signals the adrenals to pump out cortisol.[vi] This, of course, is a natural response but maintaining healthy levels of cortisol is critical for maintaining good health.[vii]

Cortisol has a number of jobs to do to aid in short term and long-term survival:

  • In the short term, cortisol helps to raise blood sugar by gluconeogenesis and insulin resistance. It achieves this by breaking down muscle tissue.[viii]
  • It also switches off most of the internal stress activators if they have been temporarily spiked by a low dose trigger like a microorganism or an allergen.[ix]
  • Cortisol switches off the activated immune system and stops the reaction.[x]
  • Cortisol switches off the inflammatory response (by the way, cortisone and hydrocortisone creams for arthritis, asthma and allergic reactions are drug versions of cortisol).[xi]
  • Cortisol stimulates the uptake (depletion) the sleepy chemical serotonin and wakes you up (good if the tiger is chasing you, bad if you want to go to sleep).[xii]
  • Cortisol raises blood pressure and blood volume through fluid retention in case of injury.[xiii] Obviously, this is not idea if you want a toned body![xiv]

The adaptogenic herbs we added to Cort-RX;

  • Schisandra chinensis
  • Ashwagandha
  • Rhodiola rosea
  • Turmeric (Curcuma longa)

Take Home Message

If you feel you have cortisol dysregulation, try to reduce the stressors in your life. Easier said than done right? If you can’t spend your days on the beach, you need to find other ways to support your body’s stress response and to help maintain healthy levels of cortisol, this is where Cort RX may assist.*

References:

 

[i] Exp Ther Med. 2016 Jan; 11(1): 353–359. Published online 2015 Nov 19. doi:  10.3892/etm.2015.2882Schisandra chinensis and Rhodiola rosea exert an anti-stress effect on the HPA axis and reduce hypothalamic c-Fos expression in rats subjected to repeated stress. NAN XIA,1 JIE LI,1 HONGWEI WANG,2 JIAN WANG,1 and YANGTIAN WANG1

[ii] Clin Sci (Lond). 2001 Dec;101(6):739-47. Cortisol increases gluconeogenesis in humans: its role in the metabolic syndrome. Khani S1, Tayek JA.

[iii] Cogn Affect Behav Neurosci. 2001 Dec;1(4):388-93. Correlation between cortisol level and serotonin uptake in patients with chronic stress and depression. Tafet GE1, Idoyaga-Vargas VP, Abulafia DP, Calandria JM, Roffman SS, Chiovetta A, Shinitzky M.

[iv] Domest Anim Endocrinol. 2016 Jul;56 Suppl:S112-20. doi: 10.1016/j.domaniend.2016.03.004. Epub 2016 Mar 31. Stress, cortisol, and obesity: a role for cortisol responsiveness in identifying individuals prone to obesity.Hewagalamulage SD1, Lee TK1, Clarke IJ1, Henry BA2.

[v] Compr Physiol. 2015 Jan;5(1):217-53. doi: 10.1002/cphy.c140019. Hypothalamus as an endocrine organ.Clarke IJ1.

[vi] Compr Physiol. 2016; 6(2): 603–621. Published online 2016 Mar 15. doi: 10.1002/cphy.c150015

Regulation of the hypothalamic-pituitary-adrenocortical stress response James P. Herman, Jessica M. McKlveen, Sriparna Ghosal, Brittany Kopp, Aynara Wulsin, Ryan Makinson, Jessie Scheimann, and Brent Myers

[vii] Domest Anim Endocrinol. 2016 Jul;56 Suppl:S112-20. doi: 10.1016/j.domaniend.2016.03.004. Epub 2016 Mar 31. Stress, cortisol, and obesity: a role for cortisol responsiveness in identifying individuals prone to obesity.Hewagalamulage SD1, Lee TK1, Clarke IJ1, Henry BA2.

[viii] Clin Sci (Lond). 2001 Dec;101(6):739-47. Cortisol increases gluconeogenesis in humans: its role in the metabolic syndrome. Khani S1, Tayek JA.

[ix] MAYER EA The neurobiology of stress and gastrointestinal disease Gut 2000;47:861-869.

[x] MAYER EA The neurobiology of stress and gastrointestinal disease Gut 2000;47:861-869.

[xi] MAYER EA The neurobiology of stress and gastrointestinal disease Gut 2000;47:861-869.

[xii] Cogn Affect Behav Neurosci. 2001 Dec;1(4):388-93. Correlation between cortisol level and serotonin uptake in patients with chronic stress and depression. Tafet GE1, Idoyaga-Vargas VP, Abulafia DP, Calandria JM, Roffman SS, Chiovetta A, Shinitzky M.

[xiii] Steroids. 1995 Jan;60(1):76-80. Mechanisms of cortisol-induced hypertension in humans. Whitworth JA1, Brown MA, Kelly JJ, Williamson PM.

[xiv] Domest Anim Endocrinol. 2016 Jul;56 Suppl:S112-20. doi: 10.1016/j.domaniend.2016.03.004. Epub 2016 Mar 31. Stress, cortisol, and obesity: a role for cortisol responsiveness in identifying individuals prone to obesity.Hewagalamulage SD1, Lee TK1, Clarke IJ1, Henry BA2.

SKU cort
Barcode # 643485990383
Brand ATP Science
Shipping Weight 0.1000kg

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